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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCC
All Species:
15.15
Human Site:
S199
Identified Species:
25.64
UniProt:
Q15814
Number Species:
13
Phosphosite Substitution
Charge Score:
0.54
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15814
NP_003183.1
346
39220
S199
Q
V
L
E
K
R
A
S
E
L
H
Q
R
D
V
Chimpanzee
Pan troglodytes
XP_518477
346
39236
S199
Q
V
L
E
K
R
A
S
E
L
H
Q
R
D
V
Rhesus Macaque
Macaca mulatta
XP_001088723
346
39322
S199
Q
V
L
E
K
R
A
S
E
L
H
Q
R
D
V
Dog
Lupus familis
XP_538923
388
42549
E241
Q
V
L
E
K
R
A
E
E
L
H
Q
R
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCN9
341
38106
E194
Q
D
L
E
K
R
A
E
E
L
H
Q
R
D
V
Rat
Rattus norvegicus
NP_001101670
340
38058
E193
Q
D
L
E
K
R
A
E
E
L
H
Q
R
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508991
335
37102
S188
R
V
L
E
K
R
A
S
E
L
L
Q
R
D
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922489
350
39443
E194
Q
V
L
V
R
Q
A
E
E
I
Q
Q
R
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722959
355
40503
A184
E
H
I
V
L
D
S
A
K
V
N
G
Q
D
I
Honey Bee
Apis mellifera
XP_001120828
342
39209
E195
E
Q
L
V
L
D
A
E
N
V
N
K
N
D
I
Nematode Worm
Caenorhab. elegans
Q27249
256
29613
T118
E
R
A
N
F
L
E
T
Q
V
D
E
A
K
V
Sea Urchin
Strong. purpuratus
XP_783718
353
39965
E206
E
N
L
S
L
S
A
E
E
I
Y
L
K
D
V
Poplar Tree
Populus trichocarpa
XP_002307082
324
36492
N177
I
L
S
K
K
F
K
N
F
K
E
I
G
E
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195702
345
38291
E194
E
T
L
V
K
S
F
E
G
S
S
I
G
E
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.3
72.9
N.A.
76
74.5
N.A.
61.5
N.A.
N.A.
43.7
N.A.
33.5
38.7
21.1
39.6
Protein Similarity:
100
99.1
97.6
78.3
N.A.
84.3
83.5
N.A.
74.5
N.A.
N.A.
64
N.A.
57.7
58
40.1
62.6
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
80
N.A.
N.A.
60
N.A.
6.6
20
6.6
33.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
93.3
N.A.
N.A.
80
N.A.
66.6
53.3
40
60
Percent
Protein Identity:
29.7
N.A.
N.A.
32.3
N.A.
N.A.
Protein Similarity:
48.2
N.A.
N.A.
51.7
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
72
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
0
15
0
0
0
0
8
0
0
79
0
% D
% Glu:
36
0
0
50
0
0
8
50
65
0
8
8
0
15
0
% E
% Phe:
0
0
0
0
8
8
8
0
8
0
0
0
0
0
15
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
8
15
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
43
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
0
0
15
0
15
0
0
29
% I
% Lys:
0
0
0
8
65
0
8
0
8
8
0
8
8
8
0
% K
% Leu:
0
8
79
0
22
8
0
0
0
50
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
0
8
8
0
15
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
50
8
0
0
0
8
0
0
8
0
8
58
8
0
0
% Q
% Arg:
8
8
0
0
8
50
0
0
0
0
0
0
58
0
0
% R
% Ser:
0
0
8
8
0
15
8
29
0
8
8
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
43
0
29
0
0
0
0
0
22
0
0
0
0
58
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _